Date: August 11, 2022
Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST)
Proteins have long been recognized as novel molecules due to their broad range of therapeutic applications. However, with the number of new and complex protein-based modalities filling development pipelines, such as conjugate, fusion, and multi-specific antibodies, complete characterization through analytical methodologies is vital to ensure the safety and efficacy of each drug candidate. These analyses include amino acid sequence confirmation, quality attribute identification and localization, determination of product & process related impurities, structural and stability testing, and much more. Biopharma 101 by SCIEX is intended to provide you with a thorough introduction to foundational analytical characterization workflows for protein therapeutics. From the basics of protein chemistry, to utilizing mass spectrometry to identify a protein’s primary sequence, capillary electrophoresis to determine product- and process-related impurities, and microfluidic modulation spectroscopy to measure functionally relevant structural changes in biomolecules; joining this class will upgrade your protein therapeutic expertise!
- How to differentiate between the various orders of protein structure
- How to identify and localize post-translation modifications with mass spectrometry
- How to determine overall product and process related impurities, including protein fragments and charge variants with capillary electrophoresis
- How to measure critical changes in protein secondary structure, which effect therapeutic efficacy and safety with microfluidic modulation spectroscopy
Webinars will be available for unlimited on-demand viewing after live event.